The National Institutes of Health recently bestowed a five-year $2.6 million grant to researchers at the University of Hawaii Cancer Center to examine the role that certain genes may play in asbestos-related cancer and whether certain cell mutations may play a role in the survival of patients. The research team will be led by esteemed researchers Michele Cabrone and Haining Yang and look into the role of the BAP1 gene in human cancer development and cell metabolism.
“This grant adds to our two already funded NIH grants and one grant from the Department of Defense, confirming the leadership of the Hawaii team as the top federally-funded research team in the U.S. to conduct research on mesothelioma, a cancer developed frequently in those exposed to asbestos,” said Carbone.
Carbone is distinguished for his discovery of the role that genes play in mesothelioma while studying a cancer epidemic in remote villages of Turkey. He and Yang further collaborated by studying mesothelioma genetics by conducting studies of families in the United States who have a high incidence of cancer, during which time they discovered a condition the pair termed “BAP1 cancer syndrome.”